GB virus type C interactions with HIV: the role of envelope glycoproteins

GB virus C: cellular interactions, HIV inhibition and natural history

GB virus C (GBV-C) is a nonpathogenic lymphotropic virus that replicates in B and T lymphocytes. Infection with GBV-C is documented worldwide and is common: between 1% and 5% of healthy blood donors are viremic at the time of donation. Antibodies to GBV-C proteins are not usually detected during viremia, and antibodies to the GBV-C envelope glycoprotein E2 develop following the clearance of vir...

Biogenesis of hepatitis C virus envelope glycoproteins.

IP: 54.191.40.80 On: Sat, 09 Sep 2017 23:23:00 Journal of General Virology (2001), 82, 2589–2595. Printed in Great Britain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...

GB virus C interactions with HIV: effects on immunoactivation and mechanisms of immunomodulation

Approved: __________________________________ Thesis Supervisor __________________________________ Title and Department __________________________________ Date 1 GB VIRUS C INTERACTIONS WITH HIV: EFFECTS ON IMMUNOACTIVATION AND MECHANISMS OF IMMUNOMODULATION

GB virus type C: a beneficial infection?

GB virus type C: a virus in search of a disease or a role in HIV therapy?

GB virus type C, first isolated in 1995, is a single-stranded RNA flavivirus that is genetically similar to hepatitis C virus (HCV) [1]. GBV-C is a relatively common infection worldwide, with up to 2% of blood donors and up to 40% of injection drug users (IDUs) in the United States demonstrating presence of GBV-C RNA in their plasma [1]. Up to 16% of healthy US blood donors and up to 70% of US ...